Sixteen-year-old physics whiz Lois wants only one thing: to travel into space. But heavy-set people like Lois don’t get to be astronauts. Though she has a genetic predisposition to be overweight, Lois starves herself to trim down — and winds up in a clinic after a series of fainting spells. Here, she meets three girls facing their own stiff challenges: Amélie suffers from gender dysphoria, Stannah is in a wheelchair, and Justine is so terrified of electromagnetic waves that she destroys whatever appliances she can get her hands on. The girls form a motley crew, but they have one thing in common: They want to get out of the clinic. And when Lois reveals her plan to make it to Toulouse to compete at a national science competition for the grand prize of a zero-gravity flight, the girls band together to break free and make a dream come true.